Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.60 |
| ▸ | CES1 | P23141 | 4/20 | 0.60 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3208067 | 0.82 | CES1 (0.52) | CES2CES1TSHRALDH1A1 | |
| Podoscyphic Acid SCHEMBL2437877 | 0.82 | CES2 (0.58) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL2437216 | 0.82 | CES2 (0.58) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL547458 | 0.82 | CES2 (0.58) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL547457 | 0.82 | CES2 (0.58) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL26463501 | 0.82 | CES1 (0.58) | CES2CES1FAAHGPR84PPARG | |
| SCHEMBL28053256 | 0.80 | FAAH (0.62) | FAAHPPARGPPARAFABP4ALOX15 | |
| SCHEMBL7952574 | 0.79 | CES2 (0.54) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL1482106 | 0.78 | TRPA1 (0.61) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11796280 | 0.78 | TRPA1 (0.61) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217804-B1 | ANALOGS OF SUBSTANCES P | ENICHEM S.p.A. (IT) | 1991-10-02 | — | — | EP | claimed |