SCHEMBL9822781

SCHEMBL9822781

NS(=O)(=O)c1ccccc1Cc1nnn[nH]1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.37
CA2 P00918 4/20 0.37
CA6 P23280 3/20 0.37
CA9 Q16790 3/20 0.37
CA4 P22748 2/20 0.37
CA12 O43570 2/20 0.37
CA5A P35218 2/20 0.37
CA7 P43166 2/20 0.37
CA5B Q9Y2D0 2/20 0.37
CYP2C9 P11712 1/20 0.37
CA14 Q9ULX7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7822927 0.79 TAAR1 (0.41) CA1CA2CA9CA12
SCHEMBL3145757 0.76 HSPA5 (0.52) CA2CA9CA12
SCHEMBL9057228 0.76 AR (0.43)
SCHEMBL2660074 0.73 ALDH1A1 (0.37)
SCHEMBL5816301 0.72 C1R (0.38) CYP2C9
SCHEMBL16946602 0.72
SCHEMBL9504728 0.71 GAA (0.53)
SCHEMBL12017477 0.70 AR (0.46)
SCHEMBL6916250 0.70 CA1 (0.40) CA1CA2CA6CA9CA4
SCHEMBL1249225 0.70 ADRA2A (0.53) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0204513-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-17 EP disclosed
US-5017214-A Herbicidal sulfonamides LEVITT GEORGE (US) 1991-05-21 US disclosed
US-4913726-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-04-03 US disclosed
US-4786311-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-22 US disclosed
US-4746353-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-24 US disclosed
EP-0204513-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-12-10 EP disclosed