Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 7/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693416 | 0.88 | KCNH2 (0.38) | TGFBR1AOC3KDRPIK3CAPIK3CB | |
| SCHEMBL1314769 | 0.71 | AOC3 (0.50) | AOC3 | |
| SCHEMBL9974286 | 0.71 | DRD2 (0.48) | ADORA2ACTSKCTSS | |
| SCHEMBL1312197 | 0.69 | L3MBTL1 (0.50) | AOC3KMT2ATLR7 | |
| SCHEMBL15318665 | 0.68 | HTR1A (0.44) | ADORA2ACTSKCTSS | |
| SCHEMBL244011 | 0.66 | CCR1 (0.46) | TGFBR1CCNE1CDK2THRBMAPK14 | |
| SCHEMBL17694455 | 0.66 | HRH3 (0.35) | TGFBR1HRH3CCNE1CDK2CTSK | |
| SCHEMBL1314155 | 0.66 | KDM4C (0.46) | HRH3AOC3 | |
| SCHEMBL23114418 | 0.65 | KCNH2 (0.46) | — | |
| SCHEMBL23114439 | 0.65 | KCNH2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217552-B1 | NOVEL PYRIDINE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND A PLANT DISEASE PROTECTANT CONTAINING THEM AS THE ACTIVE INGREDIENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-04-03 | — | — | EP | claimed |
| US-4769376-A | Certain tri- or tetra-substituted pyridyl-1,2,4-triazoles useful as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-06 | — | — | US | claimed |
| EP-0217552-A2 | Novel pyridine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-08 | — | — | EP | claimed |
| US-4769376-A | Certain tri- or tetra-substituted pyridyl-1,2,4-triazoles useful as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-06 | — | — | US | disclosed |
| EP-0217552-A2 | Novel pyridine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-08 | — | — | EP | disclosed |