Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822796 | 0.88 | TGFBR1 (0.41) | CTSKCTSSADORA2AADORA2BAOC3 | |
| SCHEMBL9822676 | 0.74 | KCNH2 (0.43) | KCNH2TGFBR1PIK3CAPIK3CB | |
| SCHEMBL9822971 | 0.71 | KCNH2 (0.49) | KCNH2TGFBR1 | |
| SCHEMBL9823113 | 0.69 | ADORA2A (0.51) | KCNH2ADORA2AADORA2BAOC3F2R | |
| SCHEMBL1314769 | 0.68 | AOC3 (0.50) | AOC3 | |
| SCHEMBL10690694 | 0.66 | KCNH2 (0.35) | KCNH2CTSKCTSSTGFBR1PIK3CA | |
| SCHEMBL10691008 | 0.66 | AOC3 (0.35) | KCNH2CTSKCTSSAOC3TGFBR1 | |
| SCHEMBL1312197 | 0.65 | L3MBTL1 (0.50) | AOC3KMT2A | |
| SCHEMBL10369402 | 0.65 | KCNH2 (0.47) | KCNH2TGFBR1 | |
| SCHEMBL1404092 | 0.65 | KCNH2 (0.83) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769376-A | Certain tri- or tetra-substituted pyridyl-1,2,4-triazoles useful as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-06 | — | — | US | disclosed |
| EP-0217552-A2 | Novel pyridine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-08 | — | — | EP | disclosed |