Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.44 |
| ▸ | CA2 | P00918 | 9/20 | 0.44 |
| ▸ | CA9 | Q16790 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822775 | 0.82 | CA1 (0.46) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL11590609 | 0.78 | ALDH1A1 (0.39) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL11590602 | 0.77 | SMN1; SMN2 (0.37) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL22635606 | 0.77 | CA12 (0.44) | CA1CA2CA9CA12HIF1A | |
| SCHEMBL17359685 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL19207105 | 0.72 | CSNK2A1 (0.45) | CA1CA9CA12ALDH1A1SMN1; SMN2 | |
| SCHEMBL9822633 | 0.71 | CA1 (0.39) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL2666044 | 0.70 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1HIF1A | |
| SCHEMBL9822973 | 0.70 | HSD11B1 (0.44) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL27311317 | 0.68 | KDM4E (0.46) | CA1CA2CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204513-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-17 | — | — | EP | disclosed |
| US-5017214-A | Herbicidal sulfonamides | LEVITT GEORGE (US) | 1991-05-21 | — | — | US | disclosed |
| US-4913726-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4786311-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| US-4746353-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| EP-0204513-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-10 | — | — | EP | disclosed |