Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822775 | 0.84 | CA1 (0.46) | HSD11B1HIF1ANPSR1RXFP1ALDH1A1 | |
| SCHEMBL22635606 | 0.76 | CA12 (0.44) | HIF1ANPSR1RXFP1HTR2CPTGS2 | |
| SCHEMBL30147353 | 0.75 | HSD11B1 (0.61) | HSD11B1SMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL22786993 | 0.74 | KCNN4 (0.47) | SMN1; SMN2HIF1ANPSR1RXFP1ALDH1A1 | |
| SCHEMBL9823087 | 0.72 | PDK2 (0.42) | HSD11B1SMN1; SMN2ALDH1A1AGTR1AGTR2 | |
| SCHEMBL20684736 | 0.71 | KCNN4 (0.54) | HSD11B1SMN1; SMN2HIF1ANPSR1RXFP1 | |
| SCHEMBL3070167 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2HIF1ANPSR1RXFP1ALDH1A1 | |
| SCHEMBL3784925 | 0.71 | KCNN4 (0.51) | SMN1; SMN2HIF1ANPSR1RXFP1ALDH1A1 | |
| SCHEMBL7127239 | 0.71 | ALDH1A1 (0.48) | HSD11B1SMN1; SMN2NPSR1ALDH1A1HTT | |
| SCHEMBL26354012 | 0.70 | P2RX7 (0.44) | SMN1; SMN2HIF1ANPSR1RXFP1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204513-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-17 | — | — | EP | disclosed |
| US-5017214-A | Herbicidal sulfonamides | LEVITT GEORGE (US) | 1991-05-21 | — | — | US | disclosed |
| US-4913726-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4786311-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| US-4746353-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| EP-0204513-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-10 | — | — | EP | disclosed |