Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 4/20 | 0.46 |
| ▸ | FLT4 | P35916 | 4/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107060 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRCASP1KDM4EMAPT | |
| SCHEMBL5732135 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRCASP1KDM4EMAPT | |
| SCHEMBL123057 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2NPC1RAB9AHPGDMEN1 | |
| SCHEMBL1164132 | 0.80 | FLT1 (0.51) | SMN1; SMN2TSHRCASP1KDM4EMAPT | |
| SCHEMBL1669829 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2TSHRCASP1KDM4EMAPT | |
| SCHEMBL11296424 | 0.73 | L3MBTL1 (0.47) | SMN1; SMN2NPC1RAB9AHPGDMEN1 | |
| SCHEMBL5080596 | 0.73 | RECQL (0.71) | SMN1; SMN2TSHRCASP1KDM4EMAPT | |
| Benzoyl Chloride SCHEMBL15512882 | 0.73 | MEN1 (0.50) | SMN1; SMN2NPC1RAB9AHPGDMEN1 | |
| SCHEMBL29829303 | 0.73 | RECQL (0.71) | SMN1; SMN2TSHRCASP1KDM4EMAPT | |
| SCHEMBL257466 | 0.72 | FLT1 (0.49) | SMN1; SMN2TSHRCASP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243982-B1 | 1-ACYL-2,3-DIHYDRO-4(1H)-QUINOLINONE-4-OXIME DERIVATIVE, PROCESS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITION AND INTERMEDIATES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-17 | — | — | EP | disclosed |