Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824359 | 0.87 | ALDH1A1 (0.39) | LMNAALDH1A1HTTKMT2AMAPT | |
| SCHEMBL9823846 | 0.85 | CCR5 (0.45) | GAAMAPT | |
| SCHEMBL9823802 | 0.81 | KMT2A (0.44) | ALDH1A1HTTKMT2ATSHRKCNMA1 | |
| SCHEMBL9823586 | 0.69 | SMN1; SMN2 (0.40) | LMNAALDH1A1HTTKMT2AGAA | |
| SCHEMBL9720636 | 0.67 | LMNA (0.65) | LMNAALDH1A1HTTKMT2ATSHR | |
| SCHEMBL10552875 | 0.64 | LMNA (0.60) | LMNAALDH1A1HTTKMT2ATSHR | |
| SCHEMBL16951330 | 0.64 | LMNA (0.56) | LMNAALDH1A1HTTKMT2ATSHR | |
| SCHEMBL6358441 | 0.63 | MAPT (0.60) | LMNAALDH1A1HTTKMT2ATSHR | |
| SCHEMBL17457926 | 0.62 | TSHR (0.51) | LMNAALDH1A1HTTKMT2ATSHR | |
| SCHEMBL11204887 | 0.62 | ALDH1A1 (0.43) | LMNAALDH1A1HTTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227100-B1 | N-VINYLIMIDAZOLES AND -TRIAZOLES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-04-03 | — | — | EP | claimed |