Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823586 | 0.88 | SMN1; SMN2 (0.40) | KMT2ASMN1; SMN2CYP19A1ALDH1A1HTT | |
| SCHEMBL9823677 | 0.81 | LMNA (0.43) | KMT2ATSHRALDH1A1HTTGRM7 | |
| SCHEMBL9824013 | 0.79 | ADRB2 (0.46) | KMT2ATSHRSMN1; SMN2ALDH1A1KCNMA1 | |
| SCHEMBL11465439 | 0.70 | CYP19A1 (0.54) | KMT2ATSHRSMN1; SMN2CYP19A1ALDH1A1 | |
| SCHEMBL9824359 | 0.69 | ALDH1A1 (0.39) | KMT2ASMN1; SMN2CYP19A1ALDH1A1HTT | |
| SCHEMBL6103175 | 0.69 | POLB (0.66) | TSHRSMN1; SMN2ALDH1A1HTTCYP1A2 | |
| SCHEMBL9823846 | 0.68 | CCR5 (0.45) | POLBMAPTGAA | |
| SCHEMBL9823697 | 0.68 | ADRB2 (0.48) | SMN1; SMN2CYP3A4MAPTCYP2C9 | |
| SCHEMBL17457926 | 0.66 | TSHR (0.51) | KMT2ATSHRALDH1A1HTTCYP2C19 | |
| SCHEMBL6358445 | 0.65 | MEN1 (0.54) | KMT2ATSHRSMN1; SMN2ALDH1A1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227100-B1 | N-VINYLIMIDAZOLES AND -TRIAZOLES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0227100-B1 | N-VINYLIMIDAZOLES AND -TRIAZOLES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-04-03 | — | — | EP | disclosed |