Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 8/20 | 0.33 |
| ▸ | CES1 | P23141 | 5/20 | 0.32 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.32 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4466465 | 0.82 | PLOD2 (0.39) | HSD17B10FAAHCES1CES2PLOD2 | |
| SCHEMBL11763114 | 0.79 | TDP1 (0.55) | HSD17B10TDP1ALDH1A1MGAMGAA | |
| SCHEMBL967731 | 0.75 | MGAM (0.55) | HSD17B10TDP1ALDH1A1MGAMGAA | |
| SCHEMBL197340 | 0.75 | MGAM (0.48) | HSD17B10FAAHCES1CES2PLOD2 | |
| SCHEMBL10690369 | 0.73 | HSD17B10 (0.48) | HSD17B10TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL28371084 | 0.72 | FAAH (0.41) | HSD17B10FAAHCES1CES2PLOD2 | |
| SCHEMBL10139381 | 0.72 | THRB (0.53) | TDP1CES2PLOD2PLOD3PLOD1 | |
| SCHEMBL12651369 | 0.71 | PLOD2 (0.39) | HSD17B10TDP1FAAHCES1CES2 | |
| SCHEMBL27628030 | 0.71 | PLOD2 (0.44) | HSD17B10FAAHCES1CES2PLOD2 | |
| SCHEMBL13696767 | 0.71 | TDP1 (0.41) | HSD17B10TDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265305-B1 | 5-PYRAZOLONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS HERBICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1991-06-12 | — | — | EP | disclosed |
| EP-0265305-A1 | 5-Pyrazolone derivatives, process for their preparation, their use as herbicides and compositions containing them | ROUSSEL-UCLAF (FR) | 1988-04-27 | — | — | EP | disclosed |