Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18538241 | 0.89 | TSHR (0.42) | CHRM2CHRM3TSHRNPSR1ALDH1A1 | |
| SCHEMBL18538246 | 0.81 | TSHR (0.39) | CHRM2CHRM3TSHRNPSR1ALDH1A1 | |
| SCHEMBL9824067 | 0.81 | TSHR (0.42) | CHRM2CHRM3TSHRNPSR1ALDH1A1 | |
| SCHEMBL17471625 | 0.81 | TSHR (0.42) | CHRM2CHRM3TSHRNPSR1ALDH1A1 | |
| SCHEMBL13077661 | 0.80 | CHRM2 (0.42) | CHRM2CHRM3TSHRNPSR1F2 | |
| SCHEMBL12600976 | 0.78 | CHRM2 (0.52) | CHRM2CHRM3TSHRNPSR1ALDH1A1 | |
| SCHEMBL14359874 | 0.78 | CHRM2 (0.35) | CHRM2CHRM3TSHRNPSR1ALDH1A1 | |
| SCHEMBL9824265 | 0.78 | TSHR (0.38) | CHRM2CHRM3TSHRNPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9823800 | 0.77 | TSHR (0.36) | CHRM2CHRM3TSHRNPSR1ALDH1A1 | |
| SCHEMBL9824007 | 0.77 | ALDH1A1 (0.43) | CHRM2CHRM3TSHRNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |