Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824184 | 0.95 | KDM4E (0.37) | TSHRUSP2HTTHSD17B10ALDH1A1 | |
| SCHEMBL9824463 | 0.94 | KDM4E (0.36) | TSHRUSP2HTTHSD17B10ALDH1A1 | |
| SCHEMBL9823819 | 0.94 | KDM4E (0.36) | TSHRUSP2HTTHSD17B10ALDH1A1 | |
| SCHEMBL9824067 | 0.90 | TSHR (0.42) | TSHRHSD17B10ALDH1A1KMT2AKDM4E | |
| SCHEMBL14359874 | 0.83 | CHRM2 (0.35) | TSHRALDH1A1KDM4ECHRM2CHRM3 | |
| SCHEMBL11057614 | 0.82 | TSHR (0.36) | TSHRALDH1A1KDM4EGRM2CHRM2 | |
| Hydrochloric Acid SCHEMBL9823800 | 0.82 | TSHR (0.36) | TSHRALDH1A1KDM4EGRM2CHRM2 | |
| SCHEMBL14359278 | 0.82 | HTR1A (0.36) | TSHRALDH1A1KDM4ECHRM2CHRM3 | |
| SCHEMBL9824052 | 0.81 | MEN1 (0.47) | TSHRALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL9823744 | 0.80 | MEN1 (0.49) | TSHRHSD17B10ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |