Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824052 | 0.89 | MEN1 (0.47) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL9823744 | 0.88 | MEN1 (0.49) | ALDH1A1KDM4ETSHRHSD17B10KMT2A | |
| SCHEMBL9824067 | 0.81 | TSHR (0.42) | ALDH1A1KDM4ETSHRHSD17B10GRM2 | |
| SCHEMBL9824265 | 0.79 | TSHR (0.38) | ALDH1A1KDM4ETSHRHSD17B10GRM2 | |
| SCHEMBL18538241 | 0.79 | TSHR (0.42) | ALDH1A1KDM4ETSHRGRM2POLB | |
| SCHEMBL9824184 | 0.77 | KDM4E (0.37) | ALDH1A1KDM4ETSHRHSD17B10GRM2 | |
| SCHEMBL9823720 | 0.77 | CHRM2 (0.49) | ALDH1A1KDM4ETSHRGRM2CHRM2 | |
| SCHEMBL9824463 | 0.76 | KDM4E (0.36) | ALDH1A1KDM4ETSHRHSD17B10GRM2 | |
| SCHEMBL9823819 | 0.76 | KDM4E (0.36) | ALDH1A1KDM4ETSHRHSD17B10GRM2 | |
| SCHEMBL14359874 | 0.75 | CHRM2 (0.35) | ALDH1A1KDM4ETSHRCHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |