Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824265 | 0.90 | TSHR (0.38) | TSHRKDM4EALDH1A1CHRM2CHRM3 | |
| SCHEMBL9824184 | 0.88 | KDM4E (0.37) | TSHRKDM4EALDH1A1CHRM2CHRM3 | |
| SCHEMBL9823819 | 0.87 | KDM4E (0.36) | TSHRKDM4EALDH1A1CHRM2CHRM3 | |
| SCHEMBL9824463 | 0.87 | KDM4E (0.36) | TSHRKDM4EALDH1A1CHRM2CHRM3 | |
| SCHEMBL18538241 | 0.83 | TSHR (0.42) | TSHRKDM4EALDH1A1CHRM2CHRM3 | |
| SCHEMBL18538246 | 0.82 | TSHR (0.39) | TSHRKDM4EALDH1A1CHRM2CHRM3 | |
| SCHEMBL9824007 | 0.81 | ALDH1A1 (0.43) | TSHRKDM4EALDH1A1CHRM2CHRM3 | |
| SCHEMBL9823720 | 0.81 | CHRM2 (0.49) | TSHRKDM4EALDH1A1CHRM2CHRM3 | |
| SCHEMBL16038492 | 0.79 | CHRM2 (0.36) | TSHRKDM4ECHRM2CHRM3GRM2 | |
| SCHEMBL14359874 | 0.79 | CHRM2 (0.35) | TSHRKDM4EALDH1A1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |