Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 4/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13296896 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1MPISMN1; SMN2 | |
| SCHEMBL6506142 | 0.80 | DAO (0.44) | KMT2AMEN1ALDH1A1GAARAB9A | |
| SCHEMBL3827647 | 0.79 | KDM4E (0.69) | KMT2AMEN1ALDH1A1MPIRAB9A | |
| SCHEMBL2880217 | 0.79 | RARA (0.66) | KMT2AMEN1ALDH1A1GAARAB9A | |
| SCHEMBL22460192 | 0.78 | CDC7 (0.67) | KMT2AMEN1ALDH1A1KDM4ERARA | |
| SCHEMBL7907788 | 0.78 | TRPM8 (0.56) | KMT2AMEN1ALDH1A1GAARAB9A | |
| SCHEMBL290278 | 0.77 | KDM4E (0.66) | KMT2AMEN1ALDH1A1MPIRAB9A | |
| SCHEMBL28485399 | 0.76 | HTR2B (0.53) | KMT2AMEN1ALDH1A1GAARAB9A | |
| SCHEMBL10552788 | 0.76 | TARBP2 (0.57) | KMT2AMEN1ALDH1A1GAARAB9A | |
| SCHEMBL19114171 | 0.75 | RAB9A (0.60) | KMT2AMEN1ALDH1A1MPIGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0262873-A1 | N-tetrazolyl thiazolecarboxamide derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |