Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL10553577 | 0.93 | RAB9A (0.53) | RAB9ANPC1POLBTLR7ALDH1A1 | |
| SCHEMBL9823541 | 0.89 | RAB9A (0.61) | RAB9ANPC1POLBTLR7ALDH1A1 | |
| SCHEMBL9823214 | 0.89 | TLR7 (0.49) | RAB9ANPC1POLBTLR7GAA | |
| SCHEMBL9823539 | 0.89 | MAPT (0.60) | RAB9ANPC1POLBTLR7GAA | |
| SCHEMBL9823477 | 0.88 | TDP1 (0.64) | RAB9ANPC1TLR7ALDH1A1GAA | |
| SCHEMBL9823576 | 0.87 | LMNA (0.50) | RAB9ANPC1POLBTLR7GAA | |
| SCHEMBL9823479 | 0.87 | TLR7 (0.61) | RAB9ANPC1POLBTLR7ALDH1A1 | |
| SCHEMBL9823285 | 0.87 | RAB9A (0.50) | RAB9ANPC1POLBTLR7ALDH1A1 | |
| SCHEMBL9823543 | 0.86 | IRAK4 (0.57) | RAB9ANPC1POLBTLR7ALDH1A1 | |
| SCHEMBL9823528 | 0.84 | IRAK4 (0.42) | RAB9ANPC1POLBTLR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |