Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.58 |
| ▸ | ATM | Q13315 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823214 | 0.90 | TLR7 (0.49) | RAB9AGAAMAPTLMNATLR7 | |
| SCHEMBL9823539 | 0.90 | MAPT (0.60) | RAB9AGAAMAPTLMNATLR7 | |
| SCHEMBL9823799 | 0.89 | RAB9A (0.61) | RAB9AGAAMAPTLMNATLR7 | |
| SCHEMBL9823477 | 0.89 | TDP1 (0.64) | RAB9AGAAMAPTLMNATLR7 | |
| SCHEMBL9823285 | 0.89 | RAB9A (0.50) | RAB9AGAAMAPTLMNATLR7 | |
| SCHEMBL9823576 | 0.86 | LMNA (0.50) | RAB9AGAAMAPTLMNATLR7 | |
| SCHEMBL9823479 | 0.86 | TLR7 (0.61) | RAB9AGAAMAPTLMNATLR7 | |
| SCHEMBL9823806 | 0.84 | MAPT (0.47) | RAB9AGAAMAPTLMNATLR7 | |
| Monoethanolamine SCHEMBL10553577 | 0.82 | RAB9A (0.53) | RAB9AGAAMAPTLMNATLR7 | |
| SCHEMBL9823593 | 0.82 | IRAK4 (0.66) | RAB9AGAAMAPTTLR7ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0262873-A1 | N-tetrazolyl thiazolecarboxamide derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |