Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824254 | 0.85 | KMT2A (0.34) | KMT2A | |
| SCHEMBL9824481 | 0.84 | LMNA (0.43) | HRH4 | |
| SCHEMBL9824884 | 0.84 | KMT2A (0.46) | KMT2A | |
| SCHEMBL9824344 | 0.84 | TNKS (0.39) | KMT2AHRH4 | |
| SCHEMBL9824747 | 0.82 | KMT2A (0.49) | KMT2AHRH4DPP4 | |
| SCHEMBL9824429 | 0.82 | KMT2A (0.45) | KMT2A | |
| SCHEMBL9824308 | 0.82 | PRKD3 (0.43) | — | |
| SCHEMBL9824259 | 0.80 | ALDH1A1 (0.47) | — | |
| SCHEMBL10573523 | 0.80 | — | — | |
| SCHEMBL6800507 | 0.76 | KMT2A (0.51) | KMT2AHRH4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227088-B1 | ISOXAZOLO-NAPHTHYRIDINE, ISOXAZOLO QUINOLINE, ISOTHIAZOLONAPHTHYRIDINE, AND ISOTHIAZOLOQUINOLINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1991-08-07 | — | — | EP | disclosed |
| US-4767762-A | Tricyclic quinoline and naphthyride antibacterials | ABBOTT LABORATORIES (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0227088-A1 | Isoxazolo-naphthyridine, isoxazolo quinoline, isothiazolonaphthyridine, and isothiazoloquinoline derivatives | ABBOTT LABORATORIES (US) | 1987-07-01 | — | — | EP | disclosed |