Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823745 | 1.00 | CYP19A1 (0.41) | CYP19A1KCNMA1ADRB2ADRB1ADRB3 | |
| SCHEMBL4286867 | 0.76 | KCNMA1 (0.52) | KCNMA1ADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL9824013 | 0.70 | ADRB2 (0.46) | KCNMA1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9823750 | 0.66 | ADRB2 (0.43) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7290470 | 0.65 | NPC1 (0.49) | MEN1HPGDKMT2AMAPTALDH1A1 | |
| SCHEMBL27848665 | 0.64 | CYP24A1 (0.43) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11702033 | 0.63 | IDO1 (0.60) | CYP19A1CYP11B1CYP11B2IDO1MEN1 | |
| SCHEMBL24438368 | 0.63 | ALDH1A1 (0.80) | KCNMA1POLBMEN1HPGDKMT2A | |
| SCHEMBL30692670 | 0.63 | ALDH1A1 (0.80) | KCNMA1POLBMEN1HPGDKMT2A | |
| SCHEMBL10504932 | 0.63 | CYP19A1 (0.44) | CYP19A1ADRB2ADRB1ADRB3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227100-B1 | N-VINYLIMIDAZOLES AND -TRIAZOLES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-04-03 | — | — | EP | disclosed |