Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823744 | 0.99 | MEN1 (0.49) | MEN1GAAKMT2APTGS1PTGS2 | |
| SCHEMBL9823770 | 0.83 | PTGS1 (0.47) | MEN1GAAKMT2APTGS1PTGS2 | |
| SCHEMBL9824463 | 0.82 | KDM4E (0.36) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL14359874 | 0.78 | CHRM2 (0.35) | KDM4EALDH1A1TSHR | |
| SCHEMBL9824067 | 0.78 | TSHR (0.42) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL26501687 | 0.72 | PTGS1 (0.53) | MEN1GAAKMT2APTGS1PTGS2 | |
| SCHEMBL9824285 | 0.71 | KMT2A (0.50) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL7463384 | 0.70 | PTGS1 (0.58) | MEN1GAAKMT2APTGS1PTGS2 | |
| SCHEMBL7259687 | 0.69 | PTGS1 (0.61) | MEN1GAAKMT2APTGS1PTGS2 | |
| SCHEMBL1618771 | 0.69 | PTGS1 (0.61) | MEN1GAAKMT2APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |