Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARD | Q03181 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824052 | 0.99 | MEN1 (0.47) | MEN1KMT2AGAAPTGS1PTGS2 | |
| SCHEMBL9823819 | 0.84 | KDM4E (0.36) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL9824463 | 0.84 | KDM4E (0.36) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL9823770 | 0.82 | PTGS1 (0.47) | MEN1KMT2AGAAPTGS1PTGS2 | |
| SCHEMBL9824265 | 0.80 | TSHR (0.38) | KMT2AGAATSHRALDH1A1KDM4E | |
| SCHEMBL11057614 | 0.79 | TSHR (0.36) | TSHRALDH1A1KDM4E | |
| SCHEMBL14359874 | 0.77 | CHRM2 (0.35) | TSHRALDH1A1KDM4E | |
| SCHEMBL9824067 | 0.77 | TSHR (0.42) | MEN1KMT2AGAATSHRALDH1A1 | |
| SCHEMBL26501687 | 0.74 | PTGS1 (0.53) | MEN1KMT2AGAAPTGS1PTGS2 | |
| SCHEMBL18538241 | 0.74 | TSHR (0.42) | TSHRALDH1A1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |