Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824052 | 0.83 | MEN1 (0.47) | PTGS1PTGS2MEN1GAAKMT2A | |
| SCHEMBL26501687 | 0.82 | PTGS1 (0.53) | PTGS1PTGS2MEN1GAAKMT2A | |
| SCHEMBL9823744 | 0.82 | MEN1 (0.49) | PTGS1PTGS2MEN1GAAKMT2A | |
| SCHEMBL26501524 | 0.81 | PTGS1 (0.45) | PTGS1PTGS2MEN1GAAKMT2A | |
| SCHEMBL26501528 | 0.81 | PTGS1 (0.45) | PTGS1PTGS2MEN1GAAKMT2A | |
| SCHEMBL9823908 | 0.80 | ALDH1A1 (0.39) | MEN1KMT2ASMN1; SMN2KDM4EHTR1A | |
| SCHEMBL22788082 | 0.78 | GAA (0.33) | PTGS1PTGS2MEN1GAAKMT2A | |
| SCHEMBL22728348 | 0.78 | KMT2A (0.50) | MEN1KMT2ASMN1; SMN2PTGDR2ALDH1A1 | |
| SCHEMBL14359588 | 0.76 | HTR1A (0.36) | SMN1; SMN2HTR1ADRD2HTR2CHTR7 | |
| SCHEMBL16038492 | 0.75 | CHRM2 (0.36) | MEN1KMT2AKDM4EHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |