Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824381 | 0.85 | ELANE (0.57) | KMT2AMEN1GAAGSK3AGSK3B | |
| SCHEMBL10862848 | 0.80 | ELANE (0.51) | KMT2AMEN1GAAGSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL9825096 | 0.79 | MAOB (0.51) | ACHE | |
| SCHEMBL18538241 | 0.75 | TSHR (0.42) | ALDH1A1TSHRNPSR1 | |
| SCHEMBL28777070 | 0.75 | KMT2A (0.51) | KMT2AMEN1GAAMAPTHSD17B10 | |
| SCHEMBL9824067 | 0.74 | TSHR (0.42) | KMT2AMEN1GAAMAPTHSD17B10 | |
| SCHEMBL9824007 | 0.74 | ALDH1A1 (0.43) | KMT2AMEN1GAAHSD17B10ALDH1A1 | |
| SCHEMBL9823720 | 0.73 | CHRM2 (0.49) | KMT2AMEN1MAPTMGLLALDH1A1 | |
| SCHEMBL31306898 | 0.72 | ALDH1A1 (0.51) | KMT2AMEN1GAAMAPTL3MBTL1 | |
| SCHEMBL14359874 | 0.72 | CHRM2 (0.35) | ALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |