Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ATF1 | P18846 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22289622 | 0.83 | GABRP (0.46) | ALDH1A1ATF1NFKB1POLQTACR1 | |
| SCHEMBL21979302 | 0.83 | HTR3E (0.53) | ALDH1A1NFKB1POLQL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL29472280 | 0.81 | GABRP (0.46) | ALDH1A1ATF1NFKB1POLQTACR1 | |
| SCHEMBL11383443 | 0.81 | ALDH1A1 (0.46) | ALDH1A1POLQFSCN1MEN1KMT2A | |
| SCHEMBL11394132 | 0.81 | ATF1 (0.40) | ALDH1A1ATF1NFKB1POLQFSCN1 | |
| SCHEMBL9823820 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KMT2A | |
| SCHEMBL22289624 | 0.77 | PYGL (0.44) | ALDH1A1ATF1NFKB1POLQTACR1 | |
| SCHEMBL2092289 | 0.74 | ATF1 (0.43) | ALDH1A1ATF1NFKB1FSCN1TACR1 | |
| SCHEMBL2092292 | 0.74 | TPMT (0.44) | ALDH1A1ATF1NFKB1FSCN1TACR1 | |
| SCHEMBL9823718 | 0.74 | TACR1 (0.57) | ALDH1A1POLQTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200134-B1 | 5,6-Dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives or salts thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4910315-A | Containing a phenyl substitution | KUMIAI CHEMICAL INDUSTRY CO. (JP) | 1990-03-20 | — | — | US | disclosed |
| US-4736038-A | IMMUNOLOGY | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| EP-0200134-A2 | 5,6-Dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives or salts thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1986-11-05 | — | — | EP | disclosed |