Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11925168 | 0.77 | TSHR (0.38) | ALDH1A1HPGDKDM4ETSHRNPSR1 | |
| SCHEMBL40439 | 0.70 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPTCYP2D6KMT2A | |
| SCHEMBL9824381 | 0.70 | ELANE (0.57) | PTGDR2NPSR1KMT2AELANE | |
| SCHEMBL9824285 | 0.68 | KMT2A (0.50) | PTGDR2ALDH1A1TSHRMAPTNPSR1 | |
| SCHEMBL9390740 | 0.67 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTCYP2D6KMT2A | |
| SCHEMBL28560386 | 0.67 | NR3C2 (0.46) | ALDH1A1HPGDMAPTCYP2D6NR3C2 | |
| SCHEMBL9824153 | 0.67 | LMNA (0.51) | ALDH1A1KDM4ETSHRMAPTKMT2A | |
| SCHEMBL31306898 | 0.67 | ALDH1A1 (0.51) | ALDH1A1KDM4ETSHRMAPTNPSR1 | |
| SCHEMBL10306123 | 0.66 | KMT2A (0.47) | ALDH1A1HPGDMAPTCYP2D6KMT2A | |
| SCHEMBL9419046 | 0.66 | MAPT (0.49) | ALDH1A1HPGDMAPTCYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |