Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824921 | 0.73 | KDM4E (0.58) | MEN1KMT2AMAPTTSHRKDM4E | |
| SCHEMBL10338929 | 0.72 | AR (0.54) | LMNAMEN1KMT2AMAPTMGLL | |
| SCHEMBL9824244 | 0.72 | ALDH1A1 (0.56) | LMNAMEN1KMT2AMAPTTSHR | |
| SCHEMBL9824381 | 0.69 | ELANE (0.57) | MEN1KMT2AMGLLELANEGAA | |
| SCHEMBL11035766 | 0.68 | MAPT (1.00) | LMNAMEN1KMT2AMAPTMGLL | |
| SCHEMBL22745995 | 0.67 | ELANE (0.62) | TSHRKDM4EALDH1A1ELANESMN1; SMN2 | |
| SCHEMBL9824280 | 0.67 | PTGDR2 (0.44) | KMT2AMAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL9824285 | 0.67 | KMT2A (0.50) | MEN1KMT2AMAPTMGLLTSHR | |
| SCHEMBL8475120 | 0.67 | MEN1 (0.52) | LMNAMEN1KMT2AMAPTMGLL | |
| SCHEMBL18538241 | 0.66 | TSHR (0.42) | LMNATSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |