Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824144 | 1.00 | LTA4H (0.36) | LTA4HALDH1A1TSHRNPSR1LMNA | |
| SCHEMBL9824780 | 0.85 | OPRD1 (0.33) | LTA4HOPRD1 | |
| SCHEMBL9824784 | 0.85 | OPRD1 (0.33) | LTA4HOPRD1 | |
| SCHEMBL9824064 | 0.83 | LTA4H (0.40) | LTA4HALDH1A1TSHRNPSR1LMNA | |
| SCHEMBL9824700 | 0.80 | S1PR1 (0.34) | TSHROPRD1 | |
| SCHEMBL18878629 | 0.78 | ALDH1A1 (0.42) | LTA4HALDH1A1TSHRNPSR1OPRD1 | |
| SCHEMBL9824251 | 0.78 | CYP1A2 (0.41) | LTA4HALDH1A1TSHRNPSR1OPRD1 | |
| SCHEMBL9824159 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TSHRNPSR1LMNAATM | |
| SCHEMBL9824151 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TSHRNPSR1LMNAATM | |
| SCHEMBL9824531 | 0.76 | OPRD1 (0.33) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273239-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4873236-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1989-10-10 | — | — | US | disclosed |
| EP-0273239-A1 | Condensed diazepinones, processes for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |