Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824780 | 1.00 | OPRD1 (0.33) | OPRD1LTA4HMEN1KMT2A | |
| SCHEMBL9824314 | 0.85 | LTA4H (0.36) | OPRD1LTA4H | |
| SCHEMBL9824144 | 0.85 | LTA4H (0.36) | OPRD1LTA4H | |
| SCHEMBL9824701 | 0.82 | OPRK1 (0.40) | OPRD1LTA4HMEN1KMT2A | |
| SCHEMBL9824540 | 0.81 | OPRD1 (0.33) | OPRD1 | |
| SCHEMBL9824531 | 0.81 | OPRD1 (0.33) | OPRD1 | |
| SCHEMBL9824700 | 0.76 | S1PR1 (0.34) | OPRD1 | |
| SCHEMBL9824846 | 0.76 | CYP1A2 (0.42) | OPRD1MEN1KMT2A | |
| SCHEMBL5014206 | 0.74 | KMT2A (0.48) | MEN1KMT2A | |
| SCHEMBL9824794 | 0.73 | TDP1 (0.34) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273239-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4873236-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1989-10-10 | — | — | US | disclosed |