Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826311 | 0.94 | CYSLTR2 (0.40) | RAB9ACYSLTR2CYSLTR1MAPTLMNA | |
| SCHEMBL9825094 | 0.77 | RAB9A (0.41) | RAB9ACYSLTR2CYSLTR1MAPTLMNA | |
| SCHEMBL10872894 | 0.72 | TDP1 (0.38) | MAPTLMNAALDH1A1KMT2ANPSR1 | |
| SCHEMBL10862507 | 0.72 | RAB9A (0.36) | RAB9ACYSLTR2CYSLTR1MAPTLMNA | |
| SCHEMBL10861403 | 0.72 | ADRB1 (0.41) | KMT2ACYP1A2 | |
| SCHEMBL10874214 | 0.69 | TDP1 (0.38) | MAPTLMNAALDH1A1KMT2ANPSR1 | |
| SCHEMBL3392997 | 0.69 | TDP1 (0.40) | MAPTLMNAALDH1A1KMT2AHPGD | |
| SCHEMBL10861464 | 0.68 | RAB9A (0.42) | RAB9ACYSLTR2CYSLTR1MAPTLMNA | |
| SCHEMBL9825289 | 0.67 | ADRB2 (0.42) | MAPTLMNAALDH1A1KMT2ACYP2D6 | |
| SCHEMBL9825128 | 0.66 | RAB9A (0.38) | RAB9ACYSLTR2CYSLTR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167371-B1 | DIHYDROPYRIDINE COMPOUNDS, THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| EP-0167371-A2 | Dihydropyridine compounds, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-01-08 | — | — | EP | disclosed |