Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824531 | 1.00 | OPRD1 (0.33) | OPRD1S1PR1S1PR3S1PR5 | |
| SCHEMBL9824818 | 0.90 | OPRD1 (0.33) | OPRD1S1PR1S1PR3S1PR5 | |
| SCHEMBL9824700 | 0.84 | S1PR1 (0.34) | OPRD1S1PR1S1PR3S1PR5 | |
| SCHEMBL9824784 | 0.81 | OPRD1 (0.33) | OPRD1 | |
| SCHEMBL9824780 | 0.81 | OPRD1 (0.33) | OPRD1 | |
| SCHEMBL9824225 | 0.79 | OPRD1 (0.35) | OPRD1S1PR1S1PR3S1PR5 | |
| SCHEMBL9824144 | 0.76 | LTA4H (0.36) | OPRD1 | |
| SCHEMBL9824314 | 0.76 | LTA4H (0.36) | OPRD1 | |
| SCHEMBL9824576 | 0.73 | OPRD1 (0.36) | OPRD1S1PR1S1PR3S1PR5 | |
| SCHEMBL9824126 | 0.72 | OPRD1 (0.33) | OPRD1S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273239-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4873236-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1989-10-10 | — | — | US | disclosed |
| EP-0273239-A1 | Condensed diazepinones, processes for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |