Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679332 | 0.83 | ADH1B (0.41) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL7125781 | 0.75 | SAT1 (0.32) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL7125784 | 0.75 | SAT1 (0.32) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL14471614 | 0.67 | SIGMAR1 (0.35) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL4749067 | 0.66 | NOS1 (0.32) | — | |
| SCHEMBL2349446 | 0.65 | — | — | |
| SCHEMBL25047164 | 0.65 | ADH1B (0.59) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL14454168 | 0.65 | HTR2C (0.33) | — | |
| SCHEMBL10700242 | 0.64 | MAN1B1 (0.32) | — | |
| SCHEMBL10470902 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273239-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0273239-A1 | Condensed diazepinones, processes for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |