Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991685 | 0.83 | RAB9A (0.72) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL9824160 | 0.82 | ALDH1A1 (0.70) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL15650312 | 0.82 | ALDH1A1 (0.70) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL6412640 | 0.81 | ALDH1A1 (0.68) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL3963003 | 0.81 | ALDH1A1 (0.68) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL4415550 | 0.80 | RAB9A (0.66) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL21789134 | 0.80 | ALDH1A1 (0.66) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL11300231 | 0.79 | ALDH1A1 (0.66) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL296937 | 0.78 | ALDH1A1 (0.64) | ALDH1A1RAB9AHTTSMN1; SMN2KMT2A | |
| SCHEMBL30131234 | 0.76 | ALDH1A1 (0.62) | ALDH1A1RAB9AHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200134-B1 | 5,6-Dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives or salts thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4910315-A | Containing a phenyl substitution | KUMIAI CHEMICAL INDUSTRY CO. (JP) | 1990-03-20 | — | — | US | disclosed |
| US-4736038-A | IMMUNOLOGY | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| EP-0200134-A2 | 5,6-Dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives or salts thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1986-11-05 | — | — | EP | disclosed |