Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959677 | 0.83 | YAP1 (0.48) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL7390057 | 0.83 | MTOR (0.55) | ALDH1A1RAB9AHTTKDM4EMTOR | |
| SCHEMBL3880049 | 0.83 | RAB9A (0.51) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL21392795 | 0.82 | TACR1 (0.52) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL3963059 | 0.81 | ALDH1A1 (0.54) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL5867397 | 0.80 | MTOR (0.49) | ALDH1A1RAB9AHTTMTORKMT2A | |
| SCHEMBL9824635 | 0.80 | ALDH1A1 (1.00) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL3965065 | 0.78 | ALDH1A1 (0.54) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL991685 | 0.78 | RAB9A (0.72) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL19013415 | 0.77 | MTOR (0.63) | ALDH1A1KDM4EMTORKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047447-A1 | CARDIAC SARCOMERE INHIBITORS | CYTOKINETICS, INC. (US) | 2020-03-05 | — | — | WO | disclosed |