Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12084775 | 0.83 | TRPV1 (0.50) | TRPV1GPR119EPHX2NR1H4NPC1 | |
| SCHEMBL2599660 | 0.80 | SMN1; SMN2 (0.63) | TRPV1EPHX2NR1H4NPC1RAB9A | |
| SCHEMBL13058340 | 0.78 | SLC6A2 (0.48) | TRPV1GPR119EPHX2NR1H4MEN1 | |
| SCHEMBL9498504 | 0.78 | CES2 (0.45) | NPC1RAB9AKMT2ATP53HPGD | |
| SCHEMBL4475347 | 0.77 | NPC1 (0.60) | TRPV1EPHX2NR1H4NPC1RAB9A | |
| SCHEMBL9247156 | 0.75 | SRD5A2 (0.50) | MEN1KMT2ATP53HPGDSMN1; SMN2 | |
| SCHEMBL9203545 | 0.75 | ESR1 (0.48) | RAB9AMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9507319 | 0.75 | ALDH1A1 (0.52) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL3874936 | 0.75 | NPSR1 (0.48) | TRPV1GPR119EPHX2NR1H4MEN1 | |
| SCHEMBL12086361 | 0.75 | MLYCD (0.63) | NPC1RAB9AMEN1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |