Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 9/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9824811 | 0.99 | MALT1 (0.41) | MALT1DRD2HTR2ADRD3MTNR1A | |
| SCHEMBL9825435 | 0.90 | SIGMAR1 (0.47) | MALT1DRD2MTNR1ASIGMAR1LMNA | |
| Hydrochloric Acid SCHEMBL9825052 | 0.89 | SIGMAR1 (0.47) | MALT1DRD2MTNR1ASIGMAR1LMNA | |
| SCHEMBL9692507 | 0.84 | MALT1 (0.43) | MALT1DRD2HTR2ADRD3MTNR1A | |
| Hydrochloric Acid SCHEMBL9692497 | 0.83 | MALT1 (0.42) | MALT1DRD2HTR2ADRD3MTNR1A | |
| SCHEMBL9824689 | 0.82 | MTNR1A (0.46) | DRD2MTNR1A | |
| SCHEMBL9824958 | 0.82 | DRD2 (0.43) | MALT1DRD2HTR2ADRD3MTNR1A | |
| SCHEMBL10515426 | 0.81 | DRD2 (0.33) | DRD2HTR2ADRD3LMNA | |
| Hydrochloric Acid SCHEMBL9825396 | 0.81 | DRD2 (0.42) | MALT1DRD2HTR2ADRD3MTNR1A | |
| Hydrochloric Acid SCHEMBL10516467 | 0.80 | DRD2 (0.33) | DRD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | claimed |
| EP-0252005-A1 | Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | claimed |
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |
| EP-0252005-A1 | Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |