Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268284 | 0.80 | CNR2 (0.38) | PTGDRPTGDR2POLBALDH1A1KDM4E | |
| SCHEMBL27463814 | 0.78 | MAPT (0.31) | ALDH1A1KDM4EHSD17B10MAPTCYP2C19 | |
| SCHEMBL8741425 | 0.77 | MAPK1 (0.44) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL519233 | 0.76 | ALDH1A1 (0.39) | GABRA1GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL1491958 | 0.76 | PARP1 (0.34) | ALDH1A1KDM4EHPGDENPP2HSD17B10 | |
| SCHEMBL8056032 | 0.75 | PTGDR (0.37) | PTGDRPTGDR2GABRA1GABRB2POLB | |
| SCHEMBL16236670 | 0.75 | KDM4E (0.32) | ALDH1A1KDM4EHPGDENPP2HSD17B10 | |
| SCHEMBL384597 | 0.75 | HTR7 (0.33) | ALDH1A1KDM4EHPGDENPP2HSD17B10 | |
| SCHEMBL11865883 | 0.75 | AKR1B1 (0.42) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8718496 | 0.72 | GABRA1 (0.48) | GABRA1GABRB2POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105800578-B | Air bubble liquid-membrane method production ultra micro, the method for nano ferric phosphate | 杨第伦 | 2018-04-24 | — | — | CN | disclosed |
| EP-0381141-A3 | NOVEL ARYL- OR HETEROARYL-1-ALKYL-PYRROLE-2-CARBOXYLIC ACID COMPOUNDS USEFUL IN TREATING INTERLEUKIN-1 MEDIATED CONDITIONS | MERRELL PHARMACEUTICALS INC. (US) | 1991-11-21 | — | — | EP | disclosed |
| EP-0381141-A2 | Novel aryl- or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds useful in treating interleukin-1 mediated conditions | MERRELL PHARMACEUTICALS INC. (US) | 1990-08-08 | — | — | EP | disclosed |
| EP-0381142-A2 | Method of using aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds in the treatment of interleukin-1 mediated conditions | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-08-08 | — | — | EP | disclosed |