SCHEMBL384597

SCHEMBL384597

NCc1cc[nH]c1C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.33
KDM4E B2RXH2 3/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 1/20 0.32
ENPP2 Q13822 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KEAP1 Q14145 1/20 0.32
NAPRT Q6XQN6 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HMGB1 P09429 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3054957 0.84 HTR7 (0.44) HTR7HSD17B10HMGB1
SCHEMBL1491958 0.81 PARP1 (0.34) KDM4EALDH1A1HPGDENPP2HSD17B10
SCHEMBL519233 0.81 ALDH1A1 (0.39) KDM4EALDH1A1HPGDENPP2HSD17B10
SCHEMBL16236670 0.79 KDM4E (0.32) KDM4EALDH1A1HPGDENPP2HSD17B10
SCHEMBL11865883 0.79 AKR1B1 (0.42) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL9825071 0.75 PTGDR (0.36) KDM4EALDH1A1HPGDENPP2HSD17B10
SCHEMBL7967187 0.75 PTPN1 (0.47) SMN1; SMN2
SCHEMBL2213722 0.73 DHODH (0.36)
SCHEMBL27591550 0.73 GABRP (0.43) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL10866762 0.72 BID (0.46) KDM4EALDH1A1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761554-A2 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME Biosource Pharm, Inc. (US) 2007-03-14 EP claimed
WO-2006083317-A2 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME BIOSOURCE PHARM, INC. (US) 2006-08-10 WO claimed
US-20260055150-A1 GRAIL-1 PEPTIDE PRODUCTS AND METHODS UNIV MICHIGAN (US) 2026-02-26 US disclosed
EP-4680108-A1 PEPTIDE MULTIMER PRODUCTS AND METHODS The Regents of The University of Michigan (US) 2026-01-21 EP disclosed
US-20250263685-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORPORATION 2025-08-21 US disclosed
US-20250263439-A1 HETERODIMERIC PEPTIDE REAGENTS AND METHODS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-08-21 US disclosed
EP-3660040-B1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2025-06-18 EP disclosed
EP-4565333-A2 GRAIL-1 PEPTIDE PRODUCTS AND METHODS Regents of the University of Michigan (US) 2025-06-11 EP disclosed
US-12269900-B2 Inhibitors of β integrin-G protein α subunit binding interactions THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-04-08 US disclosed
US-20250073355-A1 CD44-BINDING PEPTIDE REAGENTS AND METHODS REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-03-06 US disclosed
US-20250051416-A1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2025-02-13 US disclosed
WO-2007098420-A2 PEPTIDES THAT BLOCK THE BINDING OF IGG TO FCRN SYNTONIX PHARMACEUTICALS, INC. (US) 2007-08-30 WO disclosed
EP-1819721-A1 MICROCIN B17 ANALOGS AND METHODS FOR THEIR PREPARATION AND USE Plant Bioscience Limited (GB) 2007-08-22 EP disclosed
CN-101010336-A Peptide antibiotics and process for preparing same BIOSOURCE PHARM INC (US) 2007-08-01 CN disclosed
EP-1761554-A2 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME Biosource Pharm, Inc. (US) 2007-03-14 EP disclosed
WO-2006083317-A9 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME BIOSOURCE PHARM INC (US) 2007-03-01 WO disclosed
WO-2006083317-A2 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME BIOSOURCE PHARM, INC. (US) 2006-08-10 WO disclosed
WO-2006054102-A1 MICROCIN B17 ANALOGS AND METHODS FOR THEIR PREPARATION AND USE PLANT BIOSCIENCE LIMITED (GB) 2006-05-26 WO disclosed
EP-1627926-A1 A method to reduce false positive results Roche Diagnostics GmbH (DE) 2006-02-22 EP disclosed
CN-1737165-A A method to reduce false positive results HOFFMANN LA ROCH (CH) 2006-02-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055150-A1 GRAIL-1 PEPTIDE PRODUCTS AND METHODS TP53, TP53BP1, DDIT3 HTR7 4529/4885KDM4E 2893/4885ALDH1A1 3552/4885
US-20250263439-A1 HETERODIMERIC PEPTIDE REAGENTS AND METHODS ERBB2, EGFR, ERBB3 HTR7 4358/4885KDM4E 4714/4885ALDH1A1 4117/4885
US-20250263685-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF MAN2B1, MAN1B1, GAA HTR7 3710/4885KDM4E 2044/4885ALDH1A1 3254/4885
US-20250051416-A1 INSULIN RECEPTOR PARTIAL AGONISTS INSR, GPR119, IRS1 HTR7 340/4885KDM4E 4815/4885ALDH1A1 4716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.