Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558176 | 0.79 | SLC6A2 (0.43) | HPGDSLC6A2SLC6A4SLC6A3GPR139 | |
| SCHEMBL9557703 | 0.78 | TSHR (0.41) | HPGDSLC6A2SLC6A4SLC6A3GPR139 | |
| SCHEMBL9825489 | 0.74 | HSP90AA1 (0.38) | HPGDGPR139KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9825414 | 0.73 | CYP2C9 (0.48) | HPGDGPR139NPC1RAB9ATSHR | |
| SCHEMBL3365999 | 0.71 | TSHR (0.52) | HPGDSLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL9826137 | 0.71 | ALDH1A1 (0.39) | HPGDALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL9825038 | 0.70 | POLB (0.50) | HPGDALDH1A1RAB9ACYP2C9HDAC1 | |
| SCHEMBL9496095 | 0.70 | MEN1 (0.51) | HPGDGPR139KDM4ENPC1RAB9A | |
| SCHEMBL11782048 | 0.69 | TSHR (0.54) | HPGDSLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL11782487 | 0.69 | TSHR (0.50) | HPGDSLC6A2SLC6A4SLC6A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |