SCHEMBL9825534

SCHEMBL9825534

CCCCCCCCCCCCCOc1ccc(C(C)C)cc2cc3ccccc3c1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.46
CNR2 P34972 3/20 0.46
CYP2C9 P11712 1/20 0.44
TLR8 Q9NR97 2/20 0.41
THRA P10827 2/20 0.41
THRB P10828 2/20 0.41
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
ALOX5 P09917 1/20 0.40
GAA P10253 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PTPN11 Q06124 1/20 0.38
FAAH O00519 1/20 0.38
MGLL Q99685 1/20 0.38
PPARG P37231 2/20 0.37
PPARA Q07869 2/20 0.37
PSEN1 P49768 1/20 0.37
PSEN2 P49810 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9824893 0.85 NCF1 (0.43) CNR1CNR2MEN1KMT2AALOX5
SCHEMBL9875961 0.83 CASR (0.35) CNR1CNR2CYP2C9TLR8THRA
SCHEMBL9825147 0.82 ALOX5 (0.37) MEN1KMT2AALOX5TDP1L3MBTL1
SCHEMBL9826355 0.80 CASR (0.38) CNR1CNR2GAATDP1L3MBTL1
SCHEMBL9825608 0.79 PTPN11 (0.33) CNR1CNR2THRATHRBMEN1
SCHEMBL9825718 0.79 PTPN11 (0.33) CNR1CNR2THRATHRBMEN1
SCHEMBL9825074 0.79 PTPN11 (0.33) CNR1CNR2THRATHRBMEN1
SCHEMBL14019084 0.79 ALOX5 (0.48) CNR1CNR2CYP2C9TLR8THRA
SCHEMBL9826194 0.78 CASR (0.38) CNR1CNR2CYP2C9TLR8MEN1
SCHEMBL9875565 0.76 PTPN11 (0.41) CNR2THRATHRBPTPN11C5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037575-A Photostability MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1991-08-06 US disclosed
EP-0187015-B1 SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME MITSUBISHI KASEI CORPORATION (JP) 1991-05-29 EP disclosed