SCHEMBL9825147

SCHEMBL9825147

COCCOCCOc1ccc(C(C)C)cc2cc3ccccc3c1-2

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.37
KDM1A O60341 3/20 0.36
KDM4E B2RXH2 4/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPK1 P28482 1/20 0.35
NCF1 P14598 3/20 0.35
BRD4 O60885 1/20 0.35
CREBBP Q92793 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KMT2A Q03164 2/20 0.34
AR P10275 1/20 0.34
MAPT P10636 2/20 0.33
MPO P05164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9824893 0.89 NCF1 (0.43) ALOX5KDM4ETDP1MAPK1NCF1
SCHEMBL9825553 0.84 DCK (0.33) BRD4CREBBPALDH1A1L3MBTL1
SCHEMBL9825534 0.82 CNR1 (0.46) ALOX5TDP1MEN1KMT2AL3MBTL1
SCHEMBL9825456 0.79 CTSA (0.33) KDM1ABRD4CREBBPALDH1A1L3MBTL1
SCHEMBL9825140 0.76 ALOX5 (0.40) ALOX5SMN1; SMN2ALDH1A1MAPT
SCHEMBL9825183 0.75 CTSA (0.35) KDM1ABRD4CREBBPSMN1; SMN2ALDH1A1
SCHEMBL9825137 0.74 MAPT (0.36) ALOX5ALDH1A1MAPTNPSR1KIF11
SCHEMBL9876138 0.73 NCF1 (0.34) NCF1SMN1; SMN2
SCHEMBL13498040 0.71 FDPS (0.49) KDM4ETDP1MAPK1SMN1; SMN2MEN1
SCHEMBL25894987 0.70 ESR1 (0.44) ALOX5KDM1AKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037575-A Photostability MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1991-08-06 US disclosed
EP-0187015-B1 SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME MITSUBISHI KASEI CORPORATION (JP) 1991-05-29 EP disclosed