SCHEMBL9824893

SCHEMBL9824893

CCOCCOc1ccc(C(C)C)cc2cc3ccccc3c1-2

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 5/20 0.43
ALOX5 P09917 1/20 0.43
KDM4E B2RXH2 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KIF11 P52732 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HTR1B P28222 2/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
S1PR1 P21453 1/20 0.33
GRM4 Q14833 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
NR2E1 Q9Y466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9825147 0.89 ALOX5 (0.37) NCF1ALOX5KDM4ESMN1; SMN2KIF11
SCHEMBL9825534 0.85 CNR1 (0.46) ALOX5MEN1KMT2AHTR1BTDP1
SCHEMBL9876138 0.83 NCF1 (0.34) NCF1SMN1; SMN2BCHEACHE
SCHEMBL9825140 0.79 ALOX5 (0.40) ALOX5SMN1; SMN2ALDH1A1S1PR1ACHE
SCHEMBL9824891 0.79 ALOX5 (0.38) ALOX5KIF11
SCHEMBL9826044 0.79 NCF1 (0.32) NCF1SMN1; SMN2BCHEACHE
SCHEMBL14288499 0.74 NCF1 (0.58) NCF1KDM4ESMN1; SMN2MEN1ALDH1A1
SCHEMBL9825553 0.73 DCK (0.33) ALDH1A1
SCHEMBL9825137 0.72 MAPT (0.36) ALOX5KIF11ALDH1A1NPSR1
SCHEMBL17811820 0.72 L3MBTL1 (0.43) KDM4ESMN1; SMN2MEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037575-A Photostability MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1991-08-06 US disclosed
EP-0187015-B1 SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME MITSUBISHI KASEI CORPORATION (JP) 1991-05-29 EP disclosed