Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.31 |
| ▸ | FABP7 | O15540 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826400 | 0.87 | SLC15A1 (0.36) | KMT2A | |
| SCHEMBL9825337 | 0.87 | SLC15A1 (0.36) | KMT2A | |
| SCHEMBL9825808 | 0.83 | SLC7A5 (0.35) | — | |
| SCHEMBL9826160 | 0.81 | SLC7A5 (0.38) | PPARG | |
| SCHEMBL9825788 | 0.78 | TGM2 (0.39) | KMT2AFABP5FABP7 | |
| SCHEMBL9826983 | 0.78 | FABP5 (0.35) | KMT2ATNFFABP5FABP7 | |
| SCHEMBL9827234 | 0.77 | FABP7 (0.35) | KMT2AFABP5FABP7CASP3 | |
| SCHEMBL9826136 | 0.77 | SLC15A1 (0.33) | — | |
| SCHEMBL9825737 | 0.75 | SLC15A1 (0.34) | KMT2A | |
| SCHEMBL9826252 | 0.72 | SMN1; SMN2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4929630-A | SKIN DISORDERS, ACNE, 4,5-DIHYDROISOOXAZOLE PEPTIDES | SYNTEX (U.S.A.) INC. (US) | 1990-05-29 | — | — | US | disclosed |
| US-4912120-A | Containing amine and amide substitution | SYNTEX (U.S.A.) INC. (US) | 1990-03-27 | — | — | US | disclosed |