Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825337 | 1.00 | SLC15A1 (0.36) | SLC15A1LTA4HABCB1LAP3ALDH1A1 | |
| SCHEMBL9826136 | 0.89 | SLC15A1 (0.33) | SLC15A1LTA4HABCB1LAP3ALDH1A1 | |
| SCHEMBL9825808 | 0.88 | SLC7A5 (0.35) | SLC15A1LTA4HALDH1A1ALPIPKM | |
| SCHEMBL9825737 | 0.87 | SLC15A1 (0.34) | SLC15A1ABCB1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9825547 | 0.87 | KMT2A (0.33) | KMT2A | |
| SCHEMBL9825861 | 0.87 | TACR1 (0.45) | LTA4HMEN1KMT2A | |
| SCHEMBL9826160 | 0.86 | SLC7A5 (0.38) | SLC15A1LTA4HALDH1A1ALPIPKM | |
| SCHEMBL9826252 | 0.85 | SMN1; SMN2 (0.34) | ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL4934993 | 0.75 | TGM2 (0.49) | SLC15A1LTA4HABCB1LAP3ALPI | |
| SCHEMBL4934061 | 0.75 | TGM2 (0.49) | SLC15A1LTA4HABCB1LAP3ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4929630-A | SKIN DISORDERS, ACNE, 4,5-DIHYDROISOOXAZOLE PEPTIDES | SYNTEX (U.S.A.) INC. (US) | 1990-05-29 | — | — | US | disclosed |
| US-4912120-A | Containing amine and amide substitution | SYNTEX (U.S.A.) INC. (US) | 1990-03-27 | — | — | US | disclosed |
| EP-0237082-A2 | 3,5-disubstituted 4,5-dihydroisoxazoles as transglutaminase inhibitors | SYNTEX (U.S.A.) INC. (US) | 1987-09-16 | — | — | EP | disclosed |