SCHEMBL9825600

SCHEMBL9825600

O=C=NS(=O)(=O)c1sccc1-c1ccon1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RAB9A P51151 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9825634 0.79 KDM4E (0.35) KDM4ENPC1ALDH1A1RAB9APOLB
SCHEMBL10932076 0.67
SCHEMBL10934086 0.67
SCHEMBL10754639 0.67 NPC1 (0.33) NPC1ALDH1A1RAB9A
SCHEMBL10986856 0.66 POLB (0.32) POLB
SCHEMBL30488012 0.63 BCAT2 (0.50) KDM4ENPC1ALDH1A1RAB9APOLB
SCHEMBL10741686 0.62 LMNA (0.30)
SCHEMBL10755861 0.61 KMT2A (0.45) KDM4ENPC1ALDH1A1RAB9APOLB
SCHEMBL6335429 0.60 KDM4E (0.31) KDM4ENPC1ALDH1A1RAB9APOLB
SCHEMBL3082762 0.58 NPC1 (0.42) KDM4ENPC1ALDH1A1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0165753-B1 HERBICIDAL THIOPHENESULFONAMIDES AND PYRIDINESULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-11 EP disclosed
US-4723988-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-02-09 US disclosed
US-4684393-A PLATN GROWTH REGULATORS E. I. DUPONT DE NEMOURS AND COMPANY (US) 1987-08-04 US disclosed
EP-0165753-A2 Herbicidal thiophenesulfonamides and pyridinesulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-12-27 EP disclosed