Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.49 |
| ▸ | SELE | P16581 | 1/20 | 0.49 |
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP12 | P39900 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825879 | 0.86 | KMT2A (0.52) | ICAM1SELEPTGIRKDRCA1 | |
| SCHEMBL10511504 | 0.80 | BCAT2 (0.48) | MAPK8ALDH1A1IKBKBKDM4EMAPT | |
| SCHEMBL7534963 | 0.76 | HPGD (0.44) | PTGIRKDRCA1CA2ALDH1A1 | |
| SCHEMBL26193556 | 0.74 | KDR (0.42) | ICAM1SELEPTGIRKDRMMP2 | |
| SCHEMBL21248523 | 0.74 | SIRT1 (0.68) | ICAM1SELEPTGIRPARP10CA1 | |
| SCHEMBL6129052 | 0.74 | PARP10 (0.78) | PTGIRPARP10CA1CA2PARP1 | |
| SCHEMBL28130086 | 0.73 | BCAT2 (0.65) | PARP10CA1CA2PARP1PARP2 | |
| SCHEMBL9334871 | 0.73 | BCAT2 (0.48) | NPC1RAB9AMAPK8ALDH1A1IKBKB | |
| SCHEMBL9826553 | 0.72 | KDR (0.46) | PTGIRKDRNPC1RAB9AALDH1A1 | |
| SCHEMBL11480785 | 0.71 | L3MBTL1 (0.51) | NPC1MAPK8ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249236-B1 | N-1H-TETRAZOL-5-YL-(5-RING)-CARBOXAMIDE-DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE, AND THE USE THEREOF | WARNER-LAMBERT COMPANY (US) | 1991-04-24 | — | — | EP | disclosed |