SCHEMBL9825665

SCHEMBL9825665

O=C(CN1CSCC1=O)N1CCSC1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 17/20 0.39
DPP7 Q9UHL4 8/20 0.37
F10 P00742 1/20 0.37
DPP8 Q6V1X1 2/20 0.36
GAA P10253 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
DPP9 Q86TI2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9826656 0.79 POLB (0.39) GAANPSR1
SCHEMBL9825652 0.79 GAA (0.54) GAANPSR1
SCHEMBL9826188 0.78 KMT2A (0.39) GAANPSR1
SCHEMBL9825251 0.76 HRH3 (0.39) GAANPSR1
SCHEMBL9825290 0.73 KMT2A (0.43) GAA
SCHEMBL9825387 0.72 MAPT (0.31)
SCHEMBL9826740 0.71 ALDH1A1 (0.55) GAA
SCHEMBL10611575 0.70 DPP4 (0.47) DPP4DPP7DPP8DPP9
SCHEMBL9825486 0.69 KMT2A (0.53)
SCHEMBL9826875 0.68 ALDH1A1 (0.56) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0203743-B1 OXOTHIAZOLIDINE COMPOUND FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-02-06 EP disclosed
US-4764514-A COGNITIONACTIVATORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-08-16 US disclosed