Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 4/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826740 | 0.76 | ALDH1A1 (0.55) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL9825505 | 0.75 | ALDH1A1 (0.60) | KMT2AALDH1A1 | |
| SCHEMBL14294137 | 0.74 | BLM (0.62) | KMT2AMEN1LMNACPB1ALDH1A1 | |
| SCHEMBL9826774 | 0.73 | PKM (0.39) | ALDH1A1HTR2AKCNH2 | |
| SCHEMBL10674133 | 0.73 | KDM4E (0.57) | KMT2AALDH1A1HSD11B1 | |
| SCHEMBL6210602 | 0.72 | L3MBTL1 (0.75) | KMT2AMEN1LMNACPB1ALDH1A1 | |
| SCHEMBL2556107 | 0.71 | CPB1 (0.67) | KMT2AMEN1CPB1ALDH1A1MGLL | |
| SCHEMBL9826656 | 0.71 | POLB (0.39) | KMT2ALMNAMAPT | |
| SCHEMBL1720183 | 0.70 | MGLL (0.82) | KMT2AMEN1CPB1ALDH1A1MGLL | |
| SCHEMBL10670461 | 0.70 | CACNA2D1 (0.61) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203743-B1 | OXOTHIAZOLIDINE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4764514-A | COGNITIONACTIVATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0203743-A1 | Oxothiazolidine compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |