Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365672 | 0.81 | ALDH1A1 (0.58) | ALDH1A1PKMGAAL3MBTL1GPR183 | |
| SCHEMBL30754624 | 0.75 | ALDH1A1 (0.69) | ALDH1A1PKMGAAL3MBTL1LMNA | |
| SCHEMBL28819243 | 0.75 | ALDH1A1 (0.69) | ALDH1A1PKMGAAL3MBTL1GPR183 | |
| SCHEMBL9826656 | 0.72 | POLB (0.39) | GAALMNA | |
| SCHEMBL1711115 | 0.71 | PKM (0.85) | ALDH1A1PKML3MBTL1LMNA | |
| SCHEMBL18711518 | 0.70 | PKM (0.71) | ALDH1A1PKMGAAL3MBTL1LMNA | |
| SCHEMBL9826774 | 0.70 | PKM (0.39) | ALDH1A1PKMGAA | |
| SCHEMBL9825652 | 0.69 | GAA (0.54) | ALDH1A1GAAL3MBTL1LMNA | |
| SCHEMBL22868456 | 0.69 | PKM (0.73) | ALDH1A1PKMGAAL3MBTL1LMNA | |
| SCHEMBL9826740 | 0.69 | ALDH1A1 (0.55) | ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203743-B1 | OXOTHIAZOLIDINE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4764514-A | COGNITIONACTIVATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0203743-A1 | Oxothiazolidine compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |