Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179624 | 0.84 | POLB (0.59) | POLBSMN1; SMN2CYP3A4CYP2C9TDP1 | |
| SCHEMBL9825480 | 0.82 | RAB9A (0.53) | POLBNPC1RAB9AKMT2AHPGD | |
| SCHEMBL9824979 | 0.80 | CTSD (0.47) | POLBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8773659 | 0.80 | POLB (0.70) | POLBCYP3A4CYP2C9 | |
| SCHEMBL10718357 | 0.76 | CYP3A4 (0.53) | POLBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9824801 | 0.76 | HDAC1 (0.44) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL9824746 | 0.75 | POLB (0.46) | POLBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9824961 | 0.74 | SMN1; SMN2 (0.49) | POLBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10720007 | 0.72 | ABCB1 (0.53) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9714356 | 0.71 | POLB (0.70) | POLBCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |