Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827209 | 0.83 | POLB (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL9826922 | 0.83 | RAB9A (0.47) | MAPTALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9771342 | 0.81 | POLB (0.46) | MAPTALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9826750 | 0.81 | MAPT (0.40) | MAPTALDH1A1SCN2AKMT2AMEN1 | |
| SCHEMBL9827161 | 0.80 | TSHR (0.50) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL9827278 | 0.78 | POLB (0.55) | MAPTALDH1A1SCN2AHTTSMN1; SMN2 | |
| SCHEMBL9771318 | 0.70 | TSHR (0.33) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9826747 | 0.68 | GAA (0.46) | MAPTALDH1A1SCN2AKMT2AMEN1 | |
| SCHEMBL9771422 | 0.68 | EP300 (0.49) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11611461 | 0.66 | SCN2A (0.67) | MAPTALDH1A1SCN2AHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243734-B1 | OPTICALLY ACTIVE HYDANTOIN | MERCK PATENT GmbH (DE) | 1991-07-17 | — | — | EP | disclosed |
| EP-0243734-A2 | Optically active hydantoin | MERCK PATENT GmbH (DE) | 1987-11-04 | — | — | EP | disclosed |